Nevirapine + Paroxetine = Precautionary

Effect on Concentration

Nevirapine
Unknown
Applies within class?
No
Paroxetine
Unknown
Applies within class?
No

Pharmacologic Effects

Nevirapine
Effect
N/A
Applies within class?
No
Paroxetine
Effect
N/A
Applies within class?
No

Interaction History

N/A

Last Updated 22-Nov-2022

Summary

Etravirine (ETV) 125mg twice daily was co-administered with paroxetine 20mg once daily. There was no significant change in the pharmacokinetic parameters of either medication; there is no dose adjustment recommended when ETV and paroxetine are co-administered.[158]

Sources

Paroxetine vs nevirapine ^

Study Design

Study Results

Study Conclusions

References

M Scholler-Gyure, TN Kakuda, B S, et al. No pharmacokinetic interaction between tmc125 (etravirine; etr) and paroxetine in hiv-negative volunteers. 11th European Aids Conference. Madrid, Spain. ; 2007.